HCSGD entry for CLK4
1. General information
| Official gene symbol | CLK4 |
|---|---|
| Entrez ID | 57396 |
| Gene full name | CDC-like kinase 4 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | ISS | molecular_function |
| GO:0004712 | Protein serine/threonine/tyrosine kinase activity | IEA | molecular_function |
| GO:0004713 | Protein tyrosine kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0043484 | Regulation of RNA splicing | IMP | biological_process |
| GO:0046777 | Protein autophosphorylation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3037697124 | 0.2164489457 | 0.9999902473 | 0.8958355031 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1890709284 |
| GSE13712_SHEAR | Up | 0.1569162842 |
| GSE13712_STATIC | Down | -0.3221782711 |
| GSE19018 | Down | -0.5200462902 |
| GSE19899_A1 | Up | 0.2041700170 |
| GSE19899_A2 | Up | 0.2357973185 |
| PubMed_21979375_A1 | Down | -0.6542082901 |
| PubMed_21979375_A2 | Up | 0.2741362628 |
| GSE35957 | Down | -0.5872504423 |
| GSE36640 | Up | 0.3468744964 |
| GSE54402 | Up | 0.0043767787 |
| GSE9593 | Down | -0.3905394891 |
| GSE43922 | Up | 0.2301017950 |
| GSE24585 | Up | 0.3567163034 |
| GSE37065 | Down | -0.2086044787 |
| GSE28863_A1 | Up | 0.4237047114 |
| GSE28863_A2 | Up | 0.1800955823 |
| GSE28863_A3 | Down | -0.3655865298 |
| GSE28863_A4 | Down | -0.3043005653 |
| GSE48662 | Down | -0.0437648466 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024782 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026138 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
