HCSGD entry for AICDA

1. General information

Official gene symbolAICDA
Entrez ID57379
Gene full nameactivation-induced cytidine deaminase
Other gene symbolsAID ARP2 CDA2 HIGM2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000178Exosome (RNase complex)IDAcellular_component
GO:0004126Cytidine deaminase activityIDA NASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006397MRNA processingIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016445Somatic diversification of immunoglobulinsIDAbiological_process
GO:0016446Somatic hypermutation of immunoglobulin genesIMPbiological_process
GO:0016814Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidinesIEAmolecular_function
GO:0030183B cell differentiationNASbiological_process
GO:0045190Isotype switchingIEAbiological_process
GO:0071222Cellular response to lipopolysaccharideIEAbiological_process
GO:0080111DNA demethylationIDAbiological_process
GO:0090310Negative regulation of methylation-dependent chromatin silencingIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74596248240.40527641810.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1484439107
GSE13712_SHEARDown-0.0944172868
GSE13712_STATICDown-0.1271131357
GSE19018Up0.0063277800
GSE19899_A1Up0.1437673199
GSE19899_A2Up0.1672557192
PubMed_21979375_A1Down-0.2320008472
PubMed_21979375_A2Up0.1606191854
GSE35957Up0.0464525578
GSE36640Up0.1103880801
GSE54402Up0.1465119423
GSE9593Up0.0999716575
GSE43922Up0.0100953411
GSE24585Up0.0635548575
GSE37065Down-0.0782880203
GSE28863_A1Down-0.4322738930
GSE28863_A2Down-0.7724757322
GSE28863_A3Up0.1986261290
GSE28863_A4Up0.0126865169
GSE48662Down-0.0660538886

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.