HCSGD entry for PTGER1


1. General information

Official gene symbolPTGER1
Entrez ID5731
Gene full nameprostaglandin E receptor 1 (subtype EP1), 42kDa
Other gene symbolsEP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004957Prostaglandin E receptor activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0032496Response to lipopolysaccharideIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59129357550.64497609510.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0919526292
GSE13712_SHEARUp0.0994646886
GSE13712_STATICUp0.0315981885
GSE19018Up0.0940866233
GSE19899_A1Up0.0154418102
GSE19899_A2Up0.0113177392
PubMed_21979375_A1Up0.0678504812
PubMed_21979375_A2Up0.0099637037
GSE35957Up0.0636728616
GSE36640Up0.1903899071
GSE54402Down-0.0786411898
GSE9593Down-0.1039249061
GSE43922Up0.1022438308
GSE24585Down-0.0158174794
GSE37065Down-0.1044269213
GSE28863_A1Down-0.2806163154
GSE28863_A2Down-0.0549996610
GSE28863_A3Up0.4064790922
GSE28863_A4Up0.1781321222
GSE48662Down-0.1820561601

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

BupivacaineDB00297 APRD00247
BimatoprostDB00905 APRD00826 | DB06863
IloprostDB01088 APRD01027

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.