HCSGD entry for SEPN1
1. General information
| Official gene symbol | SEPN1 |
|---|---|
| Entrez ID | 57190 |
| Gene full name | selenoprotein N, 1 |
| Other gene symbols | CFTD MDRS1 RSMD1 RSS SELN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2567739562 | 0.0275011284 | 0.9497677487 | 0.3156787271 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2086035844 |
| GSE13712_SHEAR | Down | -1.2249200601 |
| GSE13712_STATIC | Down | -0.5746895056 |
| GSE19018 | Up | 0.3712852372 |
| GSE19899_A1 | Down | -0.3494509258 |
| GSE19899_A2 | Down | -0.2105153518 |
| PubMed_21979375_A1 | Down | -0.2882443153 |
| PubMed_21979375_A2 | Up | 0.5397679326 |
| GSE35957 | Down | -0.5311517182 |
| GSE36640 | Up | 0.2555688371 |
| GSE54402 | Down | -0.6550888475 |
| GSE9593 | Up | 0.6954589994 |
| GSE43922 | Down | -0.3893266925 |
| GSE24585 | Down | -0.3694888127 |
| GSE37065 | Down | -0.3412498880 |
| GSE28863_A1 | Up | 0.9021789745 |
| GSE28863_A2 | Up | 1.0190661699 |
| GSE28863_A3 | Up | 0.0245972272 |
| GSE28863_A4 | Down | -0.3221283913 |
| GSE48662 | Up | 0.1778474997 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016424 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038142 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042527 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043560 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045474 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
