HCSGD entry for THOC2
1. General information
| Official gene symbol | THOC2 |
|---|---|
| Entrez ID | 57187 |
| Gene full name | THO complex 2 |
| Other gene symbols | CXorf3 THO2 dJ506G2.1 hTREX120 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000346 | Transcription export complex | IDA | cellular_component |
| GO:0000347 | THO complex | IDA | cellular_component |
| GO:0000445 | THO complex part of transcription export complex | IDA | cellular_component |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0006406 | MRNA export from nucleus | IDA | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0016973 | Poly(A)+ mRNA export from nucleus | IDA | biological_process |
| GO:0046784 | Viral mRNA export from host cell nucleus | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0611567494 | 0.8944284678 | 0.5354932491 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0067486766 |
| GSE13712_SHEAR | Up | 0.2049498950 |
| GSE13712_STATIC | Up | 0.0454246506 |
| GSE19018 | Down | -0.0653789659 |
| GSE19899_A1 | Up | 0.2928871410 |
| GSE19899_A2 | Up | 0.4842240014 |
| PubMed_21979375_A1 | Up | 0.3669108620 |
| PubMed_21979375_A2 | Up | 0.5845492927 |
| GSE35957 | Down | -0.2034996863 |
| GSE36640 | Down | -0.3464545763 |
| GSE54402 | Up | 0.1592379763 |
| GSE9593 | Down | -0.3452754459 |
| GSE43922 | Down | -0.0120925733 |
| GSE24585 | Up | 0.1737300015 |
| GSE37065 | Up | 0.1081802827 |
| GSE28863_A1 | Up | 0.9330834764 |
| GSE28863_A2 | Up | 0.9225972948 |
| GSE28863_A3 | Down | -0.3445330720 |
| GSE28863_A4 | Up | 0.2237610530 |
| GSE48662 | Down | -0.0498194687 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-218-5p | MIMAT0000275 | MIRT024250 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025327 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030768 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-1180-3p | MIMAT0005825 | MIRT035917 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036819 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047168 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
