HCSGD entry for RALGAPA2
1. General information
| Official gene symbol | RALGAPA2 |
|---|---|
| Entrez ID | 57186 |
| Gene full name | Ral GTPase activating protein, alpha subunit 2 (catalytic) |
| Other gene symbols | AS250 C20orf74 bA287B20.1 dJ1049G11 dJ1049G11.4 p220 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IBA IEA | molecular_function |
| GO:0005634 | Nucleus | IBA IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | IBA | cellular_component |
| GO:0017123 | Ral GTPase activator activity | ISS | molecular_function |
| GO:0032859 | Activation of Ral GTPase activity | IBA ISS | biological_process |
| GO:0046982 | Protein heterodimerization activity | ISS | molecular_function |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6857485240 | 0.5077125869 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0327379173 |
| GSE13712_SHEAR | Down | -0.3617903060 |
| GSE13712_STATIC | Down | -0.2294127557 |
| GSE19018 | Up | 0.1123152313 |
| GSE19899_A1 | Up | 0.0742637537 |
| GSE19899_A2 | Down | -0.0854110781 |
| PubMed_21979375_A1 | Down | -0.0297637313 |
| PubMed_21979375_A2 | Up | 0.1178502876 |
| GSE35957 | Up | 0.0139236304 |
| GSE36640 | Up | 0.0137480894 |
| GSE54402 | Down | -0.0116477773 |
| GSE9593 | Down | -0.2339752469 |
| GSE43922 | Up | 0.0297559557 |
| GSE24585 | Down | -0.1110974912 |
| GSE37065 | Up | 0.3559764586 |
| GSE28863_A1 | Up | 0.2385519803 |
| GSE28863_A2 | Up | 0.2054709484 |
| GSE28863_A3 | Down | -0.3914140485 |
| GSE28863_A4 | Down | -0.0245749934 |
| GSE48662 | Down | -0.0927929518 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018712 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051870 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
