HCSGD entry for JPH2

1. General information

Official gene symbolJPH2
Entrez ID57158
Gene full namejunctophilin 2
Other gene symbolsCMH17 JP-2 JP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0014701Junctional sarcoplasmic reticulum membraneTAScellular_component
GO:0015278Calcium-release channel activityIDAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0030018Z discIEAcellular_component
GO:0030314Junctional membrane complexIEAcellular_component
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0055024Regulation of cardiac muscle tissue developmentIEAbiological_process
GO:0055074Calcium ion homeostasisIDAbiological_process
GO:0055085Transmembrane transportIDAbiological_process
GO:0060314Regulation of ryanodine-sensitive calcium-release channel activityTASbiological_process
GO:0060316Positive regulation of ryanodine-sensitive calcium-release channel activityIDAbiological_process
GO:0060402Calcium ion transport into cytosolTASbiological_process
GO:0070588Calcium ion transmembrane transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96655271460.12178100000.99999024730.6700246028

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3203672571
GSE13712_SHEARUp0.0200990769
GSE13712_STATICUp0.0454210892
GSE19018Down-0.1777467826
GSE19899_A1Up0.0886731397
GSE19899_A2Down-0.0709616419
PubMed_21979375_A1Down-0.0861549781
PubMed_21979375_A2Down-0.1746315264
GSE35957Up0.1210273257
GSE36640Down-0.0328992823
GSE54402Down-0.0391194879
GSE9593Up0.0063207168
GSE43922Up0.0234256437
GSE24585Up0.0082272530
GSE37065Down-0.0570037050
GSE28863_A1Down-0.4414158831
GSE28863_A2Down-0.6576234371
GSE28863_A3Down-0.0780414960
GSE28863_A4Up0.0337573807
GSE48662Down-0.1076106692

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.