HCSGD entry for REXO4
1. General information
| Official gene symbol | REXO4 |
|---|---|
| Entrez ID | 57109 |
| Gene full name | REX4, RNA exonuclease 4 homolog (S. cerevisiae) |
| Other gene symbols | REX4 XPMC2 XPMC2H |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | NAS | molecular_function |
| GO:0004527 | Exonuclease activity | IEA | molecular_function |
| GO:0005634 | Nucleus | NAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0467557198 | 0.3602731735 | 0.4786687281 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5380145603 |
| GSE13712_SHEAR | Down | -0.0702888642 |
| GSE13712_STATIC | Down | -0.0357604379 |
| GSE19018 | Down | -0.1359110427 |
| GSE19899_A1 | Up | 0.0274192708 |
| GSE19899_A2 | Up | 0.6140291574 |
| PubMed_21979375_A1 | Up | 1.1433652279 |
| PubMed_21979375_A2 | Up | 0.5477668250 |
| GSE35957 | Down | -0.1143305075 |
| GSE36640 | Up | 0.1928448754 |
| GSE54402 | Up | 0.4441624972 |
| GSE9593 | Down | -0.0186975633 |
| GSE43922 | Up | 0.3552614256 |
| GSE24585 | Down | -0.5733806598 |
| GSE37065 | Down | -0.2120888339 |
| GSE28863_A1 | Down | -0.6532495625 |
| GSE28863_A2 | Up | 0.0242231231 |
| GSE28863_A3 | Up | 0.0971988044 |
| GSE28863_A4 | Down | -0.1172244201 |
| GSE48662 | Up | 0.4962307417 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028599 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040143 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041926 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
