HCSGD entry for C12orf5
1. General information
| Official gene symbol | C12orf5 |
|---|---|
| Entrez ID | 57103 |
| Gene full name | chromosome 12 open reading frame 5 |
| Other gene symbols | FR2BP TIGAR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
Not in the Gene Ontology4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0008830857 | 0.9941414308 | 0.0816242105 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.7468551552 |
| GSE13712_SHEAR | Up | 0.8583042058 |
| GSE13712_STATIC | Up | 0.8057676652 |
| GSE19018 | Up | 0.0539638083 |
| GSE19899_A1 | Up | 0.9401485169 |
| GSE19899_A2 | Up | 1.0995777022 |
| PubMed_21979375_A1 | Up | 1.0152349689 |
| PubMed_21979375_A2 | Up | 1.0481007929 |
| GSE35957 | Up | 0.2954130094 |
| GSE36640 | Up | 1.6206133602 |
| GSE54402 | Up | 0.1866457965 |
| GSE9593 | Up | 0.0667788157 |
| GSE43922 | Up | 0.3478580423 |
| GSE24585 | Up | 0.3574026754 |
| GSE37065 | Up | 0.3349614946 |
| GSE28863_A1 | Down | -0.3820369987 |
| GSE28863_A2 | Up | 0.0700129462 |
| GSE28863_A3 | Up | 0.1761262167 |
| GSE28863_A4 | Up | 0.1246312916 |
| GSE48662 | Up | 0.5395134360 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025394 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030058 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041240 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 19710698 | Furthermore, knockdown of Tp53-induced glycolysis and apoptosis regulator (TIGAR), a novel target gene of p53, by small interfering RNA(siRNA) indicated its important role in the induction of cellular senescence |
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