HCSGD entry for TOMM22
1. General information
| Official gene symbol | TOMM22 |
|---|---|
| Entrez ID | 56993 |
| Gene full name | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| Other gene symbols | 1C9-2 MST065 MSTP065 TOM22 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005742 | Mitochondrial outer membrane translocase complex | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0006626 | Protein targeting to mitochondrion | TAS | biological_process |
| GO:0008320 | Protein transmembrane transporter activity | ISS TAS | molecular_function |
| GO:0016021 | Integral component of membrane | IDA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0045040 | Protein import into mitochondrial outer membrane | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5744583299 | 0.1524642947 | 0.9999902473 | 0.7543860338 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2334843916 |
| GSE13712_SHEAR | Up | 0.0784434048 |
| GSE13712_STATIC | Down | -0.1788772564 |
| GSE19018 | Down | -0.2820518279 |
| GSE19899_A1 | Down | -0.1189015169 |
| GSE19899_A2 | Down | -0.1570059286 |
| PubMed_21979375_A1 | Up | 0.0237188403 |
| PubMed_21979375_A2 | Down | -0.0816641184 |
| GSE35957 | Down | -0.4026436297 |
| GSE36640 | Down | -0.5422751092 |
| GSE54402 | Up | 0.2119647425 |
| GSE9593 | Down | -0.3228093058 |
| GSE43922 | Up | 0.0148266856 |
| GSE24585 | Down | -0.4568125375 |
| GSE37065 | Down | -0.2992404527 |
| GSE28863_A1 | Up | 0.4005951909 |
| GSE28863_A2 | Up | 0.0022076994 |
| GSE28863_A3 | Up | 0.3639133036 |
| GSE28863_A4 | Up | 0.1674293279 |
| GSE48662 | Down | -0.1312241956 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT030384 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038383 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048629 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
