HCSGD entry for ATXN7L3
1. General information
| Official gene symbol | ATXN7L3 |
|---|---|
| Entrez ID | 56970 |
| Gene full name | ataxin 7-like 3 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000124 | SAGA complex | IDA | cellular_component |
| GO:0003713 | Transcription coactivator activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016578 | Histone deubiquitination | IDA | biological_process |
| GO:0030374 | Ligand-dependent nuclear receptor transcription coactivator activity | IDA | molecular_function |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0071819 | DUBm complex | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4373152350 | 0.5262081456 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1585384200 |
| GSE13712_SHEAR | Up | 0.2112396681 |
| GSE13712_STATIC | Down | -0.0663507965 |
| GSE19018 | Down | -0.1790587580 |
| GSE19899_A1 | Up | 0.0197993201 |
| GSE19899_A2 | Up | 0.4227842724 |
| PubMed_21979375_A1 | Up | 0.3608861207 |
| PubMed_21979375_A2 | Up | 0.3243703037 |
| GSE35957 | Down | -0.2214058079 |
| GSE36640 | Down | -0.2422356779 |
| GSE54402 | Up | 0.2229509302 |
| GSE9593 | Up | 0.0670210084 |
| GSE43922 | Up | 0.1705615772 |
| GSE24585 | Down | -0.2938984794 |
| GSE37065 | Down | -0.1387547836 |
| GSE28863_A1 | Down | -0.0954966806 |
| GSE28863_A2 | Down | -0.2676116401 |
| GSE28863_A3 | Down | -0.4242619924 |
| GSE28863_A4 | Up | 0.0423726063 |
| GSE48662 | Up | 0.2838488434 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT032069 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-766-3p | MIMAT0003888 | MIRT039025 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040185 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041527 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041671 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045707 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046807 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
