HCSGD entry for ARNTL2
1. General information
| Official gene symbol | ARNTL2 |
|---|---|
| Entrez ID | 56938 |
| Gene full name | aryl hydrocarbon receptor nuclear translocator-like 2 |
| Other gene symbols | BMAL2 CLIF MOP9 PASD9 bHLHe6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000982 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity | IDA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA IEA NAS | molecular_function |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA IEA NAS | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0007623 | Circadian rhythm | IDA | biological_process |
| GO:0009649 | Entrainment of circadian clock | NAS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0190471107 | 0.1837499107 | 0.3364691275 | 0.8312962186 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0236179243 |
| GSE13712_SHEAR | Up | 0.3348676105 |
| GSE13712_STATIC | Up | 0.1812878869 |
| GSE19018 | Down | -0.0728414124 |
| GSE19899_A1 | Up | 0.4970254609 |
| GSE19899_A2 | Up | 1.1521000074 |
| PubMed_21979375_A1 | Up | 1.9454927679 |
| PubMed_21979375_A2 | Down | -0.1866130322 |
| GSE35957 | Down | -0.7950039025 |
| GSE36640 | Down | -1.0123408741 |
| GSE54402 | Up | 1.5554253652 |
| GSE9593 | Down | -0.2848454056 |
| GSE43922 | Up | 0.3062687426 |
| GSE24585 | Down | -0.2083751522 |
| GSE37065 | Up | 0.2229100677 |
| GSE28863_A1 | Down | -0.5800608357 |
| GSE28863_A2 | Up | 0.8676480701 |
| GSE28863_A3 | Down | -0.6978641879 |
| GSE28863_A4 | Up | 0.2673657186 |
| GSE48662 | Down | -0.2505397355 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016419 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-375 | MIMAT0000728 | MIRT019814 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026501 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
