HCSGD entry for NCLN
1. General information
| Official gene symbol | NCLN |
|---|---|
| Entrez ID | 56926 |
| Gene full name | nicalin |
| Other gene symbols | NET59 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008233 | Peptidase activity | IEA | molecular_function |
| GO:0009966 | Regulation of signal transduction | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1153549029 | 0.5561545078 | 0.6975089364 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1894011037 |
| GSE13712_SHEAR | Up | 0.1290313007 |
| GSE13712_STATIC | Up | 0.1694632841 |
| GSE19018 | Up | 0.0050849733 |
| GSE19899_A1 | Up | 0.2327283143 |
| GSE19899_A2 | Up | 0.6453446679 |
| PubMed_21979375_A1 | Up | 0.5856419688 |
| PubMed_21979375_A2 | Up | 0.9262304829 |
| GSE35957 | Down | -0.1788502231 |
| GSE36640 | Up | 0.1257836849 |
| GSE54402 | Up | 0.0825108777 |
| GSE9593 | Up | 0.0041615791 |
| GSE43922 | Up | 0.5536654590 |
| GSE24585 | Down | -0.8042268619 |
| GSE37065 | Down | -0.2283049791 |
| GSE28863_A1 | Down | -0.0368402991 |
| GSE28863_A2 | Up | 0.2657291850 |
| GSE28863_A3 | Down | -0.1388173732 |
| GSE28863_A4 | Down | -0.0247316388 |
| GSE48662 | Down | -0.3931700922 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-769-5p | MIMAT0003886 | MIRT039162 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039945 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043508 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051553 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
