HCSGD entry for PAK6
1. General information
Official gene symbol | PAK6 |
---|---|
Entrez ID | 56924 |
Gene full name | p21 protein (Cdc42/Rac)-activated kinase 6 |
Other gene symbols | PAK5 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0000278 | Mitotic cell cycle | IBA | biological_process |
GO:0004672 | Protein kinase activity | IEA | molecular_function |
GO:0004702 | Receptor signaling protein serine/threonine kinase activity | IBA | molecular_function |
GO:0005524 | ATP binding | IEA | molecular_function |
GO:0005634 | Nucleus | IEA | cellular_component |
GO:0005737 | Cytoplasm | IBA | cellular_component |
GO:0006355 | Regulation of transcription, DNA-templated | TAS | biological_process |
GO:0006915 | Apoptotic process | TAS | biological_process |
GO:0007010 | Cytoskeleton organization | TAS | biological_process |
GO:0007165 | Signal transduction | IBA | biological_process |
GO:0023014 | Signal transduction by phosphorylation | IBA | biological_process |
GO:0035556 | Intracellular signal transduction | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.2846227917 | 0.9506769918 | 0.9837894288 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Down | -0.0156625135 |
GSE13712_SHEAR | Down | -0.3008108638 |
GSE13712_STATIC | Up | 0.0185684249 |
GSE19018 | Up | 0.0152382436 |
GSE19899_A1 | Up | 0.1271953984 |
GSE19899_A2 | Up | 0.2311958685 |
PubMed_21979375_A1 | Down | -0.1462582160 |
PubMed_21979375_A2 | Up | 0.0233646677 |
GSE35957 | Down | -0.0049843925 |
GSE36640 | Up | 0.0866616532 |
GSE54402 | Up | 0.1350599004 |
GSE9593 | Down | -0.1040800308 |
GSE43922 | Up | 0.0390320212 |
GSE24585 | Up | 0.3065461883 |
GSE37065 | Up | 0.0469724789 |
GSE28863_A1 | Down | -0.0382258041 |
GSE28863_A2 | Up | 0.4114466746 |
GSE28863_A3 | Up | 0.2433685066 |
GSE28863_A4 | Up | 0.3261131780 |
GSE48662 | Up | 0.0121983573 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-215-5p | MIMAT0000272 | MIRT024945 | Microarray | Functional MTI (Weak) | 19074876 |
hsa-miR-192-5p | MIMAT0000222 | MIRT026453 | Microarray | Functional MTI (Weak) | 19074876 |
hsa-miR-26b-5p | MIMAT0000083 | MIRT029237 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord