HCSGD entry for AGPAT4
1. General information
| Official gene symbol | AGPAT4 |
|---|---|
| Entrez ID | 56895 |
| Gene full name | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| Other gene symbols | 1-AGPAT4 LPAAT-delta dJ473J16.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity | NAS | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006654 | Phosphatidic acid biosynthetic process | TAS | biological_process |
| GO:0008654 | Phospholipid biosynthetic process | NAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016024 | CDP-diacylglycerol biosynthetic process | IEA | biological_process |
| GO:0016746 | Transferase activity, transferring acyl groups | IEA | molecular_function |
| GO:0019432 | Triglyceride biosynthetic process | TAS | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9934587174 | 0.0104745184 | 0.9999902473 | 0.2018300146 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2940434540 |
| GSE13712_SHEAR | Down | -0.3231971858 |
| GSE13712_STATIC | Down | -0.0833817206 |
| GSE19018 | Down | -0.1645910943 |
| GSE19899_A1 | Down | -0.0674727281 |
| GSE19899_A2 | Down | -1.0769920266 |
| PubMed_21979375_A1 | Down | -1.0259297181 |
| PubMed_21979375_A2 | Down | -0.5660674609 |
| GSE35957 | Down | -0.7298020514 |
| GSE36640 | Down | -1.2080631371 |
| GSE54402 | Down | -0.1521069830 |
| GSE9593 | Down | -0.8156943661 |
| GSE43922 | Down | -0.0145776135 |
| GSE24585 | Down | -0.3128271036 |
| GSE37065 | Down | -0.0576178536 |
| GSE28863_A1 | Up | 0.1035928638 |
| GSE28863_A2 | Up | 0.0569886012 |
| GSE28863_A3 | Up | 0.0096084831 |
| GSE28863_A4 | Down | -0.0387822565 |
| GSE48662 | Down | -0.1043430642 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018200 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036864 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
