HCSGD entry for INPP5E

1. General information

Official gene symbolINPP5E
Entrez ID56623
Gene full nameinositol polyphosphate-5-phosphatase, 72 kDa
Other gene symbolsCORS1 CPD4 JBTS1 MORMS PPI5PIV
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004439Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activityIEAmolecular_function
GO:0004445Inositol-polyphosphate 5-phosphatase activityTASmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005930AxonemeIDAcellular_component
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006661Phosphatidylinositol biosynthetic processTASbiological_process
GO:0008150Biological_processNDbiological_process
GO:0032580Golgi cisterna membraneIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046855Inositol phosphate dephosphorylationIEAbiological_process
GO:0046856Phosphatidylinositol dephosphorylationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69653539000.38543643100.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1828101070
GSE13712_SHEARDown-0.2470335694
GSE13712_STATICDown-0.2094355967
GSE19018Down-0.0334874113
GSE19899_A1Down-0.0144348917
GSE19899_A2Up0.1377368557
PubMed_21979375_A1Up0.0078433128
PubMed_21979375_A2Up0.5672296511
GSE35957Down-0.5805052056
GSE36640Down-0.3176753576
GSE54402Up0.1861331392
GSE9593Up0.0205096265
GSE43922Up0.0387817625
GSE24585Down-0.3211576011
GSE37065Up0.0288904236
GSE28863_A1Up0.0677454374
GSE28863_A2Down-0.0445928571
GSE28863_A3Down-0.0072800162
GSE28863_A4Down-0.1307790427
GSE48662Up0.2070106267

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-425-5pMIMAT0003393MIRT039344CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.