HCSGD entry for ERO1LB
1. General information
| Official gene symbol | ERO1LB |
|---|---|
| Entrez ID | 56605 |
| Gene full name | ERO1-like beta (S. cerevisiae) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003756 | Protein disulfide isomerase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IEA TAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0016491 | Oxidoreductase activity | NAS | molecular_function |
| GO:0016671 | Oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | IEA | molecular_function |
| GO:0051082 | Unfolded protein binding | NAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0310110710 | 0.2946929676 | 0.4074579341 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1438839162 |
| GSE13712_SHEAR | Down | -0.9098093526 |
| GSE13712_STATIC | Down | -0.5026273524 |
| GSE19018 | Down | -0.0366234338 |
| GSE19899_A1 | Up | 0.2589062219 |
| GSE19899_A2 | Up | 0.2287650475 |
| PubMed_21979375_A1 | Up | 0.7613827183 |
| PubMed_21979375_A2 | Up | 0.6153377363 |
| GSE35957 | Down | -0.5823871988 |
| GSE36640 | Up | 1.1253806535 |
| GSE54402 | Up | 0.6741645824 |
| GSE9593 | Up | 0.2739685219 |
| GSE43922 | Up | 0.2432539057 |
| GSE24585 | Up | 0.7108558100 |
| GSE37065 | Up | 0.2019614199 |
| GSE28863_A1 | Up | 0.1475235794 |
| GSE28863_A2 | Up | 0.2354181334 |
| GSE28863_A3 | Down | -0.1746389789 |
| GSE28863_A4 | Down | -0.5898997426 |
| GSE48662 | Down | -0.0460521776 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 1-Ethyl-Pyrrolidine-2,5-Dione | DB01902 | EXPT02325 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016891 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-33a-5p | MIMAT0000091 | MIRT028200 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036896 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038553 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
