HCSGD entry for KLK7
1. General information
| Official gene symbol | KLK7 |
|---|---|
| Entrez ID | 5650 |
| Gene full name | kallikrein-related peptidase 7 |
| Other gene symbols | PRSS6 SCCE hK7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008236 | Serine-type peptidase activity | TAS | molecular_function |
| GO:0008544 | Epidermis development | TAS | biological_process |
| GO:0097209 | Epidermal lamellar body | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6865753847 | 0.8672475400 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0501404135 |
| GSE13712_SHEAR | Up | 0.1162210004 |
| GSE13712_STATIC | Up | 0.0124015068 |
| GSE19018 | Up | 0.1944962607 |
| GSE19899_A1 | Down | -0.0147548552 |
| GSE19899_A2 | Up | 0.1377507640 |
| PubMed_21979375_A1 | Up | 0.0002556964 |
| PubMed_21979375_A2 | Down | -0.1236482933 |
| GSE35957 | Up | 0.1668321180 |
| GSE36640 | Up | 0.1366350493 |
| GSE54402 | Up | 0.0121344977 |
| GSE9593 | Up | 0.0883046307 |
| GSE43922 | Up | 0.0144841640 |
| GSE24585 | Up | 0.1464343072 |
| GSE37065 | Up | 0.0050467755 |
| GSE28863_A1 | Up | 0.0419839432 |
| GSE28863_A2 | Down | -0.2324801026 |
| GSE28863_A3 | Up | 0.0604488407 |
| GSE28863_A4 | Up | 0.1191895134 |
| GSE48662 | Down | -0.0384298286 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide | DB08038 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018481 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 6621064 | Binding of thyroid hormone by heme proteins may signal protein age |
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