HCSGD entry for LRRC8A
1. General information
| Official gene symbol | LRRC8A |
|---|---|
| Entrez ID | 56262 |
| Gene full name | leucine rich repeat containing 8 family, member A |
| Other gene symbols | AGM5 LRRC8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002329 | Pre-B cell differentiation | ISS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0867141712 | 0.4340108734 | 0.6175334686 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0862488473 |
| GSE13712_SHEAR | Down | -0.1328307768 |
| GSE13712_STATIC | Down | -0.2397982064 |
| GSE19018 | Down | -1.0016032155 |
| GSE19899_A1 | Up | 0.3418306373 |
| GSE19899_A2 | Up | 0.6128433114 |
| PubMed_21979375_A1 | Up | 0.8225299653 |
| PubMed_21979375_A2 | Up | 0.9461250978 |
| GSE35957 | Up | 0.0040570866 |
| GSE36640 | Up | 0.1637340236 |
| GSE54402 | Up | 0.7163161109 |
| GSE9593 | Up | 0.0816580958 |
| GSE43922 | Up | 0.4688535921 |
| GSE24585 | Up | 0.1085818891 |
| GSE37065 | Up | 0.1261397962 |
| GSE28863_A1 | Up | 0.0274790420 |
| GSE28863_A2 | Down | -0.3109052636 |
| GSE28863_A3 | Down | -0.4567428074 |
| GSE28863_A4 | Down | -0.1668588732 |
| GSE48662 | Down | -0.1214841644 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001358 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-1 | MIMAT0000416 | MIRT001358 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT001358 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016581 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018758 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-33a-5p | MIMAT0000091 | MIRT028222 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032470 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045587 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051458 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
