HCSGD entry for PROP1

1. General information

Official gene symbolPROP1
Entrez ID5626
Gene full namePROP paired-like homeobox 1
Other gene symbolsCPHD2 PROP-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0000976Transcription regulatory region sequence-specific DNA bindingIEAmolecular_function
GO:0001568Blood vessel developmentIEAbiological_process
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0007417Central nervous system developmentTASbiological_process
GO:0008013Beta-catenin bindingIEAmolecular_function
GO:0008022Protein C-terminus bindingIEAmolecular_function
GO:0009953Dorsal/ventral pattern formationIEAbiological_process
GO:0016477Cell migrationIEAbiological_process
GO:0021979Hypothalamus cell differentiationIEAbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0048850Hypophysis morphogenesisIEAbiological_process
GO:0060070Canonical Wnt signaling pathwayIEAbiological_process
GO:0060126Somatotropin secreting cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45747899400.85891094180.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1037077984
GSE13712_SHEARUp0.0455499962
GSE13712_STATICDown-0.0585534158
GSE19018Up0.2194163079
GSE19899_A1Down-0.0898533995
GSE19899_A2Up0.0434321700
PubMed_21979375_A1Up0.0927087937
PubMed_21979375_A2Up0.0360322131
GSE35957Up0.1283318191
GSE36640Down-0.1731598866
GSE54402Down-0.1077550838
GSE9593Up0.0346222776
GSE43922Up0.1542442411
GSE24585Up0.1015809382
GSE37065Down-0.0622558947
GSE28863_A1Up0.0065985206
GSE28863_A2Up0.1461612705
GSE28863_A3Up0.3341914608
GSE28863_A4Up0.1238834117
GSE48662Up0.0562961308

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.