HCSGD entry for DNAJC3
1. General information
| Official gene symbol | DNAJC3 |
|---|---|
| Entrez ID | 5611 |
| Gene full name | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| Other gene symbols | ERdj6 HP58 P58 P58IPK PRKRI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004860 | Protein kinase inhibitor activity | TAS | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0006469 | Negative regulation of protein kinase activity | TAS | biological_process |
| GO:0006987 | Activation of signaling protein activity involved in unfolded protein response | TAS | biological_process |
| GO:0030968 | Endoplasmic reticulum unfolded protein response | TAS | biological_process |
| GO:0042326 | Negative regulation of phosphorylation | TAS | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0760803769 | 0.6089286463 | 0.5832200349 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2585149012 |
| GSE13712_SHEAR | Down | -0.0943799074 |
| GSE13712_STATIC | Down | -0.0178362529 |
| GSE19018 | Down | -0.4747617144 |
| GSE19899_A1 | Down | -0.2128212721 |
| GSE19899_A2 | Down | -0.2661146243 |
| PubMed_21979375_A1 | Down | -0.4753198197 |
| PubMed_21979375_A2 | Up | 0.0350617283 |
| GSE35957 | Up | 0.8630089802 |
| GSE36640 | Up | 0.8973191724 |
| GSE54402 | Up | 0.2953519450 |
| GSE9593 | Up | 0.2050465417 |
| GSE43922 | Down | -0.0265088778 |
| GSE24585 | Up | 0.4436390295 |
| GSE37065 | Up | 0.2468161357 |
| GSE28863_A1 | Up | 0.0551102347 |
| GSE28863_A2 | Up | 0.4742554828 |
| GSE28863_A3 | Down | -0.4929214656 |
| GSE28863_A4 | Up | 0.0630101675 |
| GSE48662 | Up | 0.3336399099 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018911 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026830 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028642 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
