HCSGD entry for PDGFC
1. General information
| Official gene symbol | PDGFC |
|---|---|
| Entrez ID | 56034 |
| Gene full name | platelet derived growth factor C |
| Other gene symbols | FALLOTEIN SCDGF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0005161 | Platelet-derived growth factor receptor binding | IEA IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0007171 | Activation of transmembrane receptor protein tyrosine kinase activity | IEA | biological_process |
| GO:0007417 | Central nervous system development | TAS | biological_process |
| GO:0008083 | Growth factor activity | IEA | molecular_function |
| GO:0009887 | Organ morphogenesis | IEA | biological_process |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0045740 | Positive regulation of DNA replication | IDA | biological_process |
| GO:0048008 | Platelet-derived growth factor receptor signaling pathway | IDA IEA | biological_process |
| GO:0048146 | Positive regulation of fibroblast proliferation | IDA | biological_process |
| GO:0050730 | Regulation of peptidyl-tyrosine phosphorylation | IEA | biological_process |
| GO:0051781 | Positive regulation of cell division | IEA | biological_process |
| GO:0071230 | Cellular response to amino acid stimulus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2631668022 | 0.1159559705 | 0.9571355070 | 0.6527110992 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4773302404 |
| GSE13712_SHEAR | Up | 0.5417607042 |
| GSE13712_STATIC | Up | 0.1600219158 |
| GSE19018 | Up | 0.1231054683 |
| GSE19899_A1 | Up | 0.4705804821 |
| GSE19899_A2 | Down | -0.4449496753 |
| PubMed_21979375_A1 | Down | -0.7203048739 |
| PubMed_21979375_A2 | Up | 0.1388752464 |
| GSE35957 | Down | -0.1410658340 |
| GSE36640 | Down | -0.0170933496 |
| GSE54402 | Down | -0.3017241723 |
| GSE9593 | Up | 0.0274041878 |
| GSE43922 | Up | 0.0002428043 |
| GSE24585 | Up | 0.1087985401 |
| GSE37065 | Up | 0.0373429122 |
| GSE28863_A1 | Down | -0.1443532979 |
| GSE28863_A2 | Up | 0.5615316428 |
| GSE28863_A3 | Down | -0.9296456180 |
| GSE28863_A4 | Up | 0.0503790015 |
| GSE48662 | Up | 0.0100056478 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019758 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022407 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025672 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040332 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
