HCSGD entry for PRKCSH


1. General information

Official gene symbolPRKCSH
Entrez ID5589
Gene full nameprotein kinase C substrate 80K-H
Other gene symbolsAGE-R2 G19P1 PCLD PKCSH PLD1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001701In utero embryonic developmentIEAbiological_process
GO:0001889Liver developmentIEAbiological_process
GO:0003723RNA bindingIEAmolecular_function
GO:0005080Protein kinase C bindingIPImolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005622IntracellularNAScellular_component
GO:0005788Endoplasmic reticulum lumenTAScellular_component
GO:0006457Protein foldingTASbiological_process
GO:0006491N-glycan processingIEAbiological_process
GO:0006807Nitrogen compound metabolic processIEAbiological_process
GO:0010977Negative regulation of neuron projection developmentIEAbiological_process
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0035556Intracellular signal transductionNASbiological_process
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0051291Protein heterooligomerizationIEAbiological_process
GO:0072001Renal system developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04869629570.46901521220.48642702091.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0953031879
GSE13712_SHEARDown-0.5235683311
GSE13712_STATICDown-0.4793710838
GSE19018Up0.4596888458
GSE19899_A1Down-0.3252240740
GSE19899_A2Up0.8382380322
PubMed_21979375_A1Up1.2153905831
PubMed_21979375_A2Up1.0930386459
GSE35957Down-0.4622792711
GSE36640Down-0.2230230371
GSE54402Down-0.1134231124
GSE9593Up0.2219662272
GSE43922Up0.0238106189
GSE24585Down-0.3708074063
GSE37065Down-0.1217047490
GSE28863_A1Up0.2706143024
GSE28863_A2Up0.0062508856
GSE28863_A3Up0.6897618619
GSE28863_A4Up0.0689451840
GSE48662Up0.6331963623

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-330-5pMIMAT0004693MIRT038254CLASHFunctional MTI (Weak)23622248
hsa-miR-454-3pMIMAT0003885MIRT039223CLASHFunctional MTI (Weak)23622248
hsa-miR-92b-3pMIMAT0003218MIRT040594CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT043014CLASHFunctional MTI (Weak)23622248
hsa-miR-342-3pMIMAT0000753MIRT043699CLASHFunctional MTI (Weak)23622248
hsa-miR-361-5pMIMAT0000703MIRT044099CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.