HCSGD entry for GABRQ
1. General information
| Official gene symbol | GABRQ |
|---|---|
| Entrez ID | 55879 |
| Gene full name | gamma-aminobutyric acid (GABA) A receptor, theta |
| Other gene symbols | THETA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004888 | Transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0004890 | GABA-A receptor activity | IEA | molecular_function |
| GO:0005230 | Extracellular ligand-gated ion channel activity | IEA | molecular_function |
| GO:0005254 | Chloride channel activity | IEA | molecular_function |
| GO:0005326 | Neurotransmitter transporter activity | TAS | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006836 | Neurotransmitter transport | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0034707 | Chloride channel complex | IEA | cellular_component |
| GO:0043235 | Receptor complex | IDA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4560206147 | 0.9004655522 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0263694011 |
| GSE13712_SHEAR | Up | 0.0129998321 |
| GSE13712_STATIC | Up | 0.1256310847 |
| GSE19018 | Down | -0.0129833449 |
| GSE19899_A1 | Up | 0.0240525492 |
| GSE19899_A2 | Up | 0.0794673083 |
| PubMed_21979375_A1 | Up | 0.0669169565 |
| PubMed_21979375_A2 | Down | -0.0294568033 |
| GSE35957 | Up | 0.0521144078 |
| GSE36640 | Up | 0.0160657225 |
| GSE54402 | Up | 0.7143326021 |
| GSE9593 | Down | -0.0509289154 |
| GSE43922 | Up | 0.0168543487 |
| GSE24585 | Down | -0.0435268375 |
| GSE37065 | Down | -0.0870637109 |
| GSE28863_A1 | Up | 0.0911206603 |
| GSE28863_A2 | Up | 0.2233212516 |
| GSE28863_A3 | Up | 0.2275299654 |
| GSE28863_A4 | Down | -0.0647058490 |
| GSE48662 | Up | 0.0009706733 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017369 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
