HCSGD entry for SLC22A11

1. General information

Official gene symbolSLC22A11
Entrez ID55867
Gene full namesolute carrier family 22 (organic anion/urate transporter), member 11
Other gene symbolsOAT4 hOAT4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005452Inorganic anion exchanger activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0008514Organic anion transmembrane transporter activityIDAmolecular_function
GO:0009897External side of plasma membraneIDAcellular_component
GO:0015347Sodium-independent organic anion transmembrane transporter activityIDAmolecular_function
GO:0015711Organic anion transportIDAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIDAcellular_component
GO:0022857Transmembrane transporter activityIEAmolecular_function
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0046415Urate metabolic processIMPbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.26628836670.95465739900.96224317681.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0599344069
GSE13712_SHEARUp0.1181487412
GSE13712_STATICUp0.1002513265
GSE19018Up0.1176810755
GSE19899_A1Up0.0868614897
GSE19899_A2Up0.1542942246
PubMed_21979375_A1Down0.0000000000
PubMed_21979375_A2Up0.0246728412
GSE35957Up0.1053304358
GSE36640Down-0.0861088688
GSE54402Up0.1708390083
GSE9593Up0.0858494654
GSE43922Up0.1143700705
GSE24585Up0.1671603614
GSE37065Down-0.0962638129
GSE28863_A1Down-0.0886086364
GSE28863_A2Up0.0611027180
GSE28863_A3Up0.2530307987
GSE28863_A4Up0.2606600536
GSE48662Up0.0188187957

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

ProbenecidDB01032 APRD00167
LesinuradDB11560 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.