HCSGD entry for EAF2
1. General information
| Official gene symbol | EAF2 |
|---|---|
| Entrez ID | 55840 |
| Gene full name | ELL associated factor 2 |
| Other gene symbols | BM040 TRAITS U19 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0030308 | Negative regulation of cell growth | IEA | biological_process |
| GO:0032783 | ELL-EAF complex | IEA | cellular_component |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0060770 | Negative regulation of epithelial cell proliferation involved in prostate gland development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8888811747 | 0.3796728316 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0444893595 |
| GSE13712_SHEAR | Down | -0.1507078802 |
| GSE13712_STATIC | Up | 0.2986968517 |
| GSE19018 | Up | 0.1670773273 |
| GSE19899_A1 | Up | 0.0403311355 |
| GSE19899_A2 | Down | -0.5017644811 |
| PubMed_21979375_A1 | Down | -0.2255557260 |
| PubMed_21979375_A2 | Down | -0.2439048948 |
| GSE35957 | Up | 0.0576267486 |
| GSE36640 | Down | -0.1964700534 |
| GSE54402 | Down | -0.0347567622 |
| GSE9593 | Down | -0.0647886715 |
| GSE43922 | Up | 0.0132820469 |
| GSE24585 | Up | 0.2471189858 |
| GSE37065 | Up | 0.0243350716 |
| GSE28863_A1 | Down | -0.2193023749 |
| GSE28863_A2 | Down | -0.1091661445 |
| GSE28863_A3 | Up | 0.1438815299 |
| GSE28863_A4 | Up | 0.0436075098 |
| GSE48662 | Down | -0.3700814372 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024640 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026244 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029057 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
