HCSGD entry for EMC3


1. General information

Official gene symbolEMC3
Entrez ID55831
Gene full nameER membrane protein complex subunit 3
Other gene symbolsPOB TMEM111
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003674Molecular_functionNDmolecular_function
GO:0008150Biological_processNDbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIDAcellular_component
GO:0072546ER membrane protein complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04607017210.92649161890.47590777081.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.6300931526
GSE13712_SHEARUp0.1597607541
GSE13712_STATICUp0.1195597423
GSE19018Down-0.1731812764
GSE19899_A1Up0.1219890887
GSE19899_A2Up0.4671116395
PubMed_21979375_A1Up0.2323768721
PubMed_21979375_A2Up0.8036796340
GSE35957Up0.0653109356
GSE36640Up1.0878136368
GSE54402Up0.0413514462
GSE9593Up0.3667180743
GSE43922Up0.4201646650
GSE24585Down-0.0109705852
GSE37065Up0.1447891757
GSE28863_A1Up0.0830073701
GSE28863_A2Down-0.0118893013
GSE28863_A3Down-0.3973430584
GSE28863_A4Down-0.1786056630
GSE48662Down-0.0230382130

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT019969MicroarrayFunctional MTI (Weak)20215506
hsa-miR-26b-5pMIMAT0000083MIRT029894MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.