HCSGD entry for EXOC2
1. General information
| Official gene symbol | EXOC2 |
|---|---|
| Entrez ID | 55770 |
| Gene full name | exocyst complex component 2 |
| Other gene symbols | SEC5 SEC5L1 Sec5p |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006887 | Exocytosis | IEA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0017160 | Ral GTPase binding | IEA | molecular_function |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0047485 | Protein N-terminus binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0486866874 | 0.9794078796 | 0.4864270209 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1091009559 |
| GSE13712_SHEAR | Up | 0.1314817533 |
| GSE13712_STATIC | Up | 0.3102188714 |
| GSE19018 | Up | 0.3068150442 |
| GSE19899_A1 | Up | 0.0775107291 |
| GSE19899_A2 | Up | 0.5834585103 |
| PubMed_21979375_A1 | Up | 0.2811141690 |
| PubMed_21979375_A2 | Up | 1.0329416265 |
| GSE35957 | Up | 0.0675969309 |
| GSE36640 | Up | 0.8316838932 |
| GSE54402 | Up | 0.2411392996 |
| GSE9593 | Up | 0.2451110174 |
| GSE43922 | Up | 0.0719881723 |
| GSE24585 | Down | -0.2068026739 |
| GSE37065 | Up | 0.1482076519 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.1855482587 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020620 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023654 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039714 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047777 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT049928 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
