HCSGD entry for POLR3E
1. General information
| Official gene symbol | POLR3E |
|---|---|
| Entrez ID | 55718 |
| Gene full name | polymerase (RNA) III (DNA directed) polypeptide E (80kD) |
| Other gene symbols | RPC5 SIN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003899 | DNA-directed RNA polymerase activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006383 | Transcription from RNA polymerase III promoter | TAS | biological_process |
| GO:0006385 | Transcription elongation from RNA polymerase III promoter | TAS | biological_process |
| GO:0006386 | Termination of RNA polymerase III transcription | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0032481 | Positive regulation of type I interferon production | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4527098287 | 0.9021964097 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0221554285 |
| GSE13712_SHEAR | Up | 0.0313454781 |
| GSE13712_STATIC | Up | 0.0988583254 |
| GSE19018 | Up | 0.2721737687 |
| GSE19899_A1 | Up | 0.0258619098 |
| GSE19899_A2 | Down | -0.0412278065 |
| PubMed_21979375_A1 | Up | 1.0880500658 |
| PubMed_21979375_A2 | Down | -0.1965247100 |
| GSE35957 | Up | 0.0913937395 |
| GSE36640 | Down | -0.2002419336 |
| GSE54402 | Up | 0.3149562721 |
| GSE9593 | Down | -0.1303229780 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0476460479 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027727 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-320a | MIMAT0000510 | MIRT044787 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT047349 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
