HCSGD entry for DOK4
1. General information
| Official gene symbol | DOK4 |
|---|---|
| Entrez ID | 55715 |
| Gene full name | docking protein 4 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000165 | MAPK cascade | IEA | biological_process |
| GO:0005057 | Receptor signaling protein activity | IEA | molecular_function |
| GO:0005158 | Insulin receptor binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0007169 | Transmembrane receptor protein tyrosine kinase signaling pathway | IEA | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8881499753 | 0.0804770184 | 0.9999902473 | 0.5366108833 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0836147984 |
| GSE13712_SHEAR | Down | -0.7630346114 |
| GSE13712_STATIC | Down | -0.4290705312 |
| GSE19018 | Up | 0.0751193429 |
| GSE19899_A1 | Down | -0.0436157614 |
| GSE19899_A2 | Up | 0.2273813985 |
| PubMed_21979375_A1 | Down | -0.4670615933 |
| PubMed_21979375_A2 | Down | -0.4711742490 |
| GSE35957 | Up | 0.1413183816 |
| GSE36640 | Up | 0.3694405951 |
| GSE54402 | Down | -0.1832578155 |
| GSE9593 | Up | 0.1418465204 |
| GSE43922 | Down | -0.0960094706 |
| GSE24585 | Up | 0.3536364832 |
| GSE37065 | Down | -0.1010094910 |
| GSE28863_A1 | Down | -0.2455226723 |
| GSE28863_A2 | Down | -0.4977436019 |
| GSE28863_A3 | Down | -0.5802101246 |
| GSE28863_A4 | Down | -0.0106889091 |
| GSE48662 | Up | 0.4924653096 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-421 | MIMAT0003339 | MIRT039377 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
