HCSGD entry for CCDC88A
1. General information
| Official gene symbol | CCDC88A |
|---|---|
| Entrez ID | 55704 |
| Gene full name | coiled-coil domain containing 88A |
| Other gene symbols | APE GIRDIN GIV GRDN HkRP1 KIAA1212 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001932 | Regulation of protein phosphorylation | ISS | biological_process |
| GO:0003779 | Actin binding | IDA IEA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006260 | DNA replication | IEA | biological_process |
| GO:0006275 | Regulation of DNA replication | IEA ISS | biological_process |
| GO:0008017 | Microtubule binding | IEA ISS | molecular_function |
| GO:0010975 | Regulation of neuron projection development | IEA ISS | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016023 | Cytoplasmic membrane-bounded vesicle | IEA | cellular_component |
| GO:0016477 | Cell migration | IEA IMP | biological_process |
| GO:0030027 | Lamellipodium | IDA | cellular_component |
| GO:0030032 | Lamellipodium assembly | IMP | biological_process |
| GO:0031410 | Cytoplasmic vesicle | IDA | cellular_component |
| GO:0031929 | TOR signaling | IEA ISS | biological_process |
| GO:0032148 | Activation of protein kinase B activity | IEA ISS | biological_process |
| GO:0032956 | Regulation of actin cytoskeleton organization | IEA IMP | biological_process |
| GO:0035091 | Phosphatidylinositol binding | IDA | molecular_function |
| GO:0042127 | Regulation of cell proliferation | IEA ISS | biological_process |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0043422 | Protein kinase B binding | IEA IPI | molecular_function |
| GO:0061024 | Membrane organization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7012897496 | 0.2575759584 | 0.9999902473 | 0.9725515421 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2752909882 |
| GSE13712_SHEAR | Up | 0.0814984277 |
| GSE13712_STATIC | Up | 0.1042568508 |
| GSE19018 | Up | 0.0070214135 |
| GSE19899_A1 | Up | 0.1519749112 |
| GSE19899_A2 | Down | -0.1876175020 |
| PubMed_21979375_A1 | Up | 0.7655280086 |
| PubMed_21979375_A2 | Up | 0.2871471895 |
| GSE35957 | Down | -0.2777602888 |
| GSE36640 | Down | -0.3852377986 |
| GSE54402 | Up | 0.0977170942 |
| GSE9593 | Down | -0.0609320072 |
| GSE43922 | Down | -0.0115706140 |
| GSE24585 | Down | -0.0146192650 |
| GSE37065 | Down | -0.0772468777 |
| GSE28863_A1 | Up | 0.0548236621 |
| GSE28863_A2 | Up | 0.4256477809 |
| GSE28863_A3 | Down | -0.5990970048 |
| GSE28863_A4 | Down | -0.1202755293 |
| GSE48662 | Down | -0.3482568950 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019700 | Microarray | Functional MTI (Weak) | 20215506 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
