HCSGD entry for SCYL2
1. General information
| Official gene symbol | SCYL2 |
|---|---|
| Entrez ID | 55681 |
| Gene full name | SCY1-like 2 (S. cerevisiae) |
| Other gene symbols | CVAK104 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002092 | Positive regulation of receptor internalization | IDA | biological_process |
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0008333 | Endosome to lysosome transport | IDA | biological_process |
| GO:0010008 | Endosome membrane | IEA | cellular_component |
| GO:0030136 | Clathrin-coated vesicle | IEA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0090090 | Negative regulation of canonical Wnt signaling pathway | IDA | biological_process |
| GO:2000286 | Receptor internalization involved in canonical Wnt signaling pathway | IDA | biological_process |
| GO:2000370 | Positive regulation of clathrin-mediated endocytosis | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7456749630 | 0.1534078796 | 0.9999902473 | 0.7558683639 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0368574520 |
| GSE13712_SHEAR | Up | 0.1560486402 |
| GSE13712_STATIC | Up | 0.1434671899 |
| GSE19018 | Down | -0.1334595277 |
| GSE19899_A1 | Up | 0.0278053035 |
| GSE19899_A2 | Down | -0.5660504996 |
| PubMed_21979375_A1 | Down | -0.4384023017 |
| PubMed_21979375_A2 | Down | -0.7752256162 |
| GSE35957 | Up | 0.3038405728 |
| GSE36640 | Up | 0.1275567396 |
| GSE54402 | Down | -0.2954781300 |
| GSE9593 | Up | 0.2269486644 |
| GSE43922 | Down | -0.2832875110 |
| GSE24585 | Up | 0.1402428721 |
| GSE37065 | Up | 0.0018745042 |
| GSE28863_A1 | Down | -0.1358204604 |
| GSE28863_A2 | Down | -0.0691663850 |
| GSE28863_A3 | Down | -0.5915611695 |
| GSE28863_A4 | Up | 0.2483241821 |
| GSE48662 | Up | 0.0037785474 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049398 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
