HCSGD entry for NPLOC4
1. General information
| Official gene symbol | NPLOC4 |
|---|---|
| Entrez ID | 55666 |
| Gene full name | nuclear protein localization 4 homolog (S. cerevisiae) |
| Other gene symbols | NPL4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | ISS | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0007030 | Golgi organization | ISS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process | ISS | biological_process |
| GO:0042175 | Nuclear outer membrane-endoplasmic reticulum membrane network | ISS | cellular_component |
| GO:0061025 | Membrane fusion | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0523021010 | 0.8969092284 | 0.5002338663 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0609988687 |
| GSE13712_SHEAR | Up | 0.1386123560 |
| GSE13712_STATIC | Up | 0.5455643514 |
| GSE19018 | Up | 0.0187021775 |
| GSE19899_A1 | Down | -0.1646613770 |
| GSE19899_A2 | Down | -0.0122617071 |
| PubMed_21979375_A1 | Up | 0.5777969905 |
| PubMed_21979375_A2 | Up | 0.9286695284 |
| GSE35957 | Down | -0.0404316068 |
| GSE36640 | Up | 0.8889722801 |
| GSE54402 | Up | 0.5902930001 |
| GSE9593 | Up | 0.0817426904 |
| GSE43922 | Up | 0.0211274027 |
| GSE24585 | Up | 0.4047670396 |
| GSE37065 | Up | 0.0203678615 |
| GSE28863_A1 | Down | -0.0459005491 |
| GSE28863_A2 | Up | 0.2490057735 |
| GSE28863_A3 | Down | -0.5693591305 |
| GSE28863_A4 | Up | 0.0913775005 |
| GSE48662 | Up | 0.2607646301 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023001 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038064 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044371 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044586 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049037 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
