HCSGD entry for ZNF446

1. General information

Official gene symbolZNF446
Entrez ID55663
Gene full namezinc finger protein 446
Other gene symbolsZKSCAN20 ZSCAN30 ZSCAN52
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000981Sequence-specific DNA binding RNA polymerase II transcription factor activityIBAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIBA IEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterIBAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIBAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82095925310.45281768930.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0662456342
GSE13712_SHEARDown-0.3296422660
GSE13712_STATICDown-0.1024534582
GSE19018Up0.1378918807
GSE19899_A1Down-0.0419126659
GSE19899_A2Up0.0644428258
PubMed_21979375_A1Down-0.1153477057
PubMed_21979375_A2Up0.0647031423
GSE35957Down-0.1497771111
GSE36640Down-0.0804766880
GSE54402Down-0.0442784643
GSE9593Down-0.0579543414
GSE43922Up0.0513683840
GSE24585Up0.1575050375
GSE37065Down-0.0261441507
GSE28863_A1Down-0.0268587439
GSE28863_A2Down-0.3730613973
GSE28863_A3Up0.1560868530
GSE28863_A4Down-0.1524634882
GSE48662Up0.1283157412

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.