HCSGD entry for PRKAB2
1. General information
| Official gene symbol | PRKAB2 |
|---|---|
| Entrez ID | 5565 |
| Gene full name | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004679 | AMP-activated protein kinase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0006633 | Fatty acid biosynthetic process | IEA | biological_process |
| GO:0006853 | Carnitine shuttle | TAS | biological_process |
| GO:0007050 | Cell cycle arrest | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008286 | Insulin receptor signaling pathway | TAS | biological_process |
| GO:0016301 | Kinase activity | IEA | molecular_function |
| GO:0016310 | Phosphorylation | IDA | biological_process |
| GO:0031588 | AMP-activated protein kinase complex | IDA | cellular_component |
| GO:0042304 | Regulation of fatty acid biosynthetic process | TAS | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0423179211 | 0.3819340907 | 0.4596987206 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4399267196 |
| GSE13712_SHEAR | Up | 0.3486618018 |
| GSE13712_STATIC | Up | 0.0761499293 |
| GSE19018 | Up | 0.4744824557 |
| GSE19899_A1 | Down | -0.0918639707 |
| GSE19899_A2 | Down | -0.2198530572 |
| PubMed_21979375_A1 | Up | 0.0816822132 |
| PubMed_21979375_A2 | Up | 0.4329067019 |
| GSE35957 | Up | 0.8022925362 |
| GSE36640 | Up | 1.0085751367 |
| GSE54402 | Down | -0.7769157950 |
| GSE9593 | Up | 0.2724658434 |
| GSE43922 | Up | 0.2022244131 |
| GSE24585 | Up | 0.7003078600 |
| GSE37065 | Down | -0.0847417394 |
| GSE28863_A1 | Up | 0.3195861044 |
| GSE28863_A2 | Up | 0.4111517941 |
| GSE28863_A3 | Down | -0.1155470354 |
| GSE28863_A4 | Down | -0.6136248300 |
| GSE48662 | Up | 0.1389967344 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-29c-3p | MIMAT0000681 | MIRT020411 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027116 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030833 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031580 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039810 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045002 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047852 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
