HCSGD entry for DEPDC1
1. General information
| Official gene symbol | DEPDC1 |
|---|---|
| Entrez ID | 55635 |
| Gene full name | DEP domain containing 1 |
| Other gene symbols | DEP.8 DEPDC1-V2 DEPDC1A SDP35 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0017053 | Transcriptional repressor complex | IDA | cellular_component |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9642886820 | 0.0000086243 | 0.9999902473 | 0.0069833333 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.4560894178 |
| GSE13712_SHEAR | Down | -0.3497303066 |
| GSE13712_STATIC | Down | -0.6934230830 |
| GSE19018 | Up | 0.1439684561 |
| GSE19899_A1 | Down | -1.5233531747 |
| GSE19899_A2 | Down | -5.3008850524 |
| PubMed_21979375_A1 | Down | -3.5482863601 |
| PubMed_21979375_A2 | Down | -7.0206769506 |
| GSE35957 | Down | -4.1435229873 |
| GSE36640 | Down | -5.1234548524 |
| GSE54402 | Down | -1.5847733119 |
| GSE9593 | Down | -1.7543194557 |
| GSE43922 | Down | -3.1843877423 |
| GSE24585 | Down | -0.0546559123 |
| GSE37065 | Down | -0.5205231991 |
| GSE28863_A1 | Down | -0.2458517360 |
| GSE28863_A2 | Up | 1.1456692543 |
| GSE28863_A3 | Down | -0.3946081376 |
| GSE28863_A4 | Up | 0.0139593378 |
| GSE48662 | Down | -0.9143156830 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002615 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002615 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-340-5p | MIMAT0004692 | MIRT019599 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT021182 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024325 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026487 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043344 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT050372 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050884 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
