HCSGD entry for ASAP3
1. General information
| Official gene symbol | ASAP3 |
|---|---|
| Entrez ID | 55616 |
| Gene full name | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| Other gene symbols | ACAP4 CENTB6 DDEFL1 UPLC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001726 | Ruffle | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005925 | Focal adhesion | IDA | cellular_component |
| GO:0008060 | ARF GTPase activator activity | IDA IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016477 | Cell migration | IMP | biological_process |
| GO:0032312 | Regulation of ARF GTPase activity | IEA | biological_process |
| GO:0032850 | Positive regulation of ARF GTPase activity | IDA | biological_process |
| GO:0051492 | Regulation of stress fiber assembly | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3616044793 | 0.0148251168 | 0.9999902473 | 0.2396723483 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2126059247 |
| GSE13712_SHEAR | Down | -1.5406661903 |
| GSE13712_STATIC | Down | -0.0996525654 |
| GSE19018 | Up | 0.1024720378 |
| GSE19899_A1 | Down | -0.1428388517 |
| GSE19899_A2 | Down | -1.0730430501 |
| PubMed_21979375_A1 | Down | -1.7758939754 |
| PubMed_21979375_A2 | Down | -0.7990015039 |
| GSE35957 | Down | -0.3830636182 |
| GSE36640 | Up | 0.1390784883 |
| GSE54402 | Down | -1.2486975136 |
| GSE9593 | Down | -0.0814118432 |
| GSE43922 | Down | -0.4071442702 |
| GSE24585 | Up | 0.6822771316 |
| GSE37065 | Down | -0.1510274611 |
| GSE28863_A1 | Up | 0.8630189978 |
| GSE28863_A2 | Up | 0.5295833177 |
| GSE28863_A3 | Up | 0.1050642722 |
| GSE28863_A4 | Down | -0.0507181801 |
| GSE48662 | Up | 0.3952130119 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018191 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
