HCSGD entry for BMP2K
1. General information
| Official gene symbol | BMP2K |
|---|---|
| Entrez ID | 55589 |
| Gene full name | BMP2 inducible kinase |
| Other gene symbols | BIKE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0019208 | Phosphatase regulator activity | IEA | molecular_function |
| GO:0030500 | Regulation of bone mineralization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0499846016 | 0.3183435812 | 0.4896391676 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1334093644 |
| GSE13712_SHEAR | Up | 0.1475478937 |
| GSE13712_STATIC | Down | -0.2212374152 |
| GSE19018 | Down | -0.5238764537 |
| GSE19899_A1 | Up | 0.3240819188 |
| GSE19899_A2 | Up | 0.9111224493 |
| PubMed_21979375_A1 | Up | 0.6522566146 |
| PubMed_21979375_A2 | Up | 1.0561326889 |
| GSE35957 | Up | 0.1800528383 |
| GSE36640 | Down | -0.6217712268 |
| GSE54402 | Up | 0.4930205113 |
| GSE9593 | Down | -0.3776432420 |
| GSE43922 | Up | 0.7996819172 |
| GSE24585 | Up | 0.0471372357 |
| GSE37065 | Up | 0.0519872406 |
| GSE28863_A1 | Up | 0.0916592474 |
| GSE28863_A2 | Up | 0.8534312796 |
| GSE28863_A3 | Down | -0.6599686176 |
| GSE28863_A4 | Down | -0.4189754572 |
| GSE48662 | Down | -0.4559810059 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026511 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027518 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051629 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-let-7i-5p | MIMAT0000415 | NA | hsa-let-7i | 19939273 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
