HCSGD entry for CNOT11
1. General information
| Official gene symbol | CNOT11 |
|---|---|
| Entrez ID | 55571 |
| Gene full name | CCR4-NOT transcription complex, subunit 11 |
| Other gene symbols | C2orf29 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000288 | Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | TAS | biological_process |
| GO:0000289 | Nuclear-transcribed mRNA poly(A) tail shortening | TAS | biological_process |
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006417 | Regulation of translation | IEA | biological_process |
| GO:0008283 | Cell proliferation | NAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0030014 | CCR4-NOT complex | IDA | cellular_component |
| GO:0031047 | Gene silencing by RNA | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8724386421 | 0.2653314654 | 0.9999902473 | 0.9867933362 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4090131517 |
| GSE13712_SHEAR | Down | -0.1373328747 |
| GSE13712_STATIC | Down | -0.0472624193 |
| GSE19018 | Up | 0.0304479101 |
| GSE19899_A1 | Down | -0.1529427281 |
| GSE19899_A2 | Up | 0.1726747605 |
| PubMed_21979375_A1 | Down | -0.0690392644 |
| PubMed_21979375_A2 | Down | -0.0554759494 |
| GSE35957 | Down | -0.2787203216 |
| GSE36640 | Down | -0.2821761281 |
| GSE54402 | Up | 0.1554136396 |
| GSE9593 | Down | -0.2764668676 |
| GSE43922 | Down | -0.0343582285 |
| GSE24585 | Up | 0.0853826168 |
| GSE37065 | Down | -0.0695856491 |
| GSE28863_A1 | Up | 0.0421301595 |
| GSE28863_A2 | Up | 0.3604092732 |
| GSE28863_A3 | Down | -0.6327126461 |
| GSE28863_A4 | Down | -0.1454619684 |
| GSE48662 | Down | -0.2056204589 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023186 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045470 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048199 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050217 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
