HCSGD entry for FEM1A
1. General information
| Official gene symbol | FEM1A |
|---|---|
| Entrez ID | 55527 |
| Gene full name | fem-1 homolog a (C. elegans) |
| Other gene symbols | EPRAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | ISS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0031867 | EP4 subtype prostaglandin E2 receptor binding | IPI | molecular_function |
| GO:0050728 | Negative regulation of inflammatory response | IDA | biological_process |
| GO:0051438 | Regulation of ubiquitin-protein ligase activity | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1021633259 | 0.5789399795 | 0.6657689775 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1709823977 |
| GSE13712_SHEAR | Up | 0.0967392683 |
| GSE13712_STATIC | Down | -0.0877704019 |
| GSE19018 | Down | -0.5469886935 |
| GSE19899_A1 | Up | 0.1028823465 |
| GSE19899_A2 | Up | 0.7398435470 |
| PubMed_21979375_A1 | Up | 1.3613554915 |
| PubMed_21979375_A2 | Up | 1.2146441289 |
| GSE35957 | Up | 0.1795660689 |
| GSE36640 | Up | 0.0051608290 |
| GSE54402 | Up | 0.2607983941 |
| GSE9593 | Down | -0.2205973837 |
| GSE43922 | Up | 0.4872639836 |
| GSE24585 | Down | -0.3170313612 |
| GSE37065 | Down | -0.1912761603 |
| GSE28863_A1 | Up | 0.1632775050 |
| GSE28863_A2 | Down | -0.1501103951 |
| GSE28863_A3 | Up | 0.2397208592 |
| GSE28863_A4 | Down | -0.0999566136 |
| GSE48662 | Up | 0.0803227884 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-760 | MIMAT0004957 | MIRT036724 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-504-5p | MIMAT0002875 | MIRT041076 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042261 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042591 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
