HCSGD entry for DHTKD1
1. General information
| Official gene symbol | DHTKD1 |
|---|---|
| Entrez ID | 55526 |
| Gene full name | dehydrogenase E1 and transketolase domain containing 1 |
| Other gene symbols | AMOXAD CMT2Q |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004591 | Oxoglutarate dehydrogenase (succinyl-transferring) activity | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006091 | Generation of precursor metabolites and energy | IMP | biological_process |
| GO:0006096 | Glycolysis | IEA | biological_process |
| GO:0006099 | Tricarboxylic acid cycle | IEA | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0030976 | Thiamine pyrophosphate binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9169400175 | 0.0250833821 | 0.9999902473 | 0.3049513626 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0043876659 |
| GSE13712_SHEAR | Up | 0.1289638076 |
| GSE13712_STATIC | Up | 0.0093366393 |
| GSE19018 | Up | 0.0649155196 |
| GSE19899_A1 | Down | -0.6507931919 |
| GSE19899_A2 | Down | -0.1518029715 |
| PubMed_21979375_A1 | Down | -1.1325973984 |
| PubMed_21979375_A2 | Down | -0.5546570757 |
| GSE35957 | Down | -0.8067537516 |
| GSE36640 | Up | 0.0355178122 |
| GSE54402 | Up | 0.0187194609 |
| GSE9593 | Down | -0.5283202336 |
| GSE43922 | Down | -0.2541714709 |
| GSE24585 | Up | 0.9594013030 |
| GSE37065 | Down | -0.1376674954 |
| GSE28863_A1 | Down | -0.1624518284 |
| GSE28863_A2 | Up | 0.0160507915 |
| GSE28863_A3 | Down | -0.8017615946 |
| GSE28863_A4 | Down | -0.0093761184 |
| GSE48662 | Down | -0.1962612780 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036136 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049034 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051121 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052332 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
