HCSGD entry for HES6
1. General information
| Official gene symbol | HES6 |
|---|---|
| Entrez ID | 55502 |
| Gene full name | hairy and enhancer of split 6 (Drosophila) |
| Other gene symbols | HES-6 bHLHb41 bHLHc23 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0003712 | Transcription cofactor activity | ISS | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005667 | Transcription factor complex | ISS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA TAS | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
| GO:0008134 | Transcription factor binding | NAS | molecular_function |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8107425668 | 0.5581444626 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0665383218 |
| GSE13712_SHEAR | Up | 0.0043090976 |
| GSE13712_STATIC | Down | -0.1119295099 |
| GSE19018 | Down | -0.0019885521 |
| GSE19899_A1 | Up | 0.0570518683 |
| GSE19899_A2 | Down | -0.1891958402 |
| PubMed_21979375_A1 | Down | -0.3364377458 |
| PubMed_21979375_A2 | Down | -0.1577158899 |
| GSE35957 | Down | -0.0778030479 |
| GSE36640 | Up | 0.0267430067 |
| GSE54402 | Down | -0.1078064130 |
| GSE9593 | Down | -0.1238686906 |
| GSE43922 | Up | 0.0441248099 |
| GSE24585 | Up | 0.2075182015 |
| GSE37065 | Up | 0.0315091489 |
| GSE28863_A1 | Down | -0.2463062560 |
| GSE28863_A2 | Down | -0.1368634376 |
| GSE28863_A3 | Up | 0.2252487052 |
| GSE28863_A4 | Up | 0.0450003472 |
| GSE48662 | Up | 0.2846417178 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024636 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026430 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-320a | MIMAT0000510 | MIRT044433 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
