HCSGD entry for AVPR2

1. General information

Official gene symbolAVPR2
Entrez ID554
Gene full namearginine vasopressin receptor 2
Other gene symbolsADHR DI1 DIR DIR3 NDI V2R
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003084Positive regulation of systemic arterial blood pressureIEAbiological_process
GO:0005000Vasopressin receptor activityIEA TASmolecular_function
GO:0005768EndosomeTAScellular_component
GO:0005783Endoplasmic reticulumTAScellular_component
GO:0005794Golgi apparatusTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006833Water transportTASbiological_process
GO:0007188Adenylate cyclase-modulating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007190Activation of adenylate cyclase activityTASbiological_process
GO:0007249I-kappaB kinase/NF-kappaB signalingIEAbiological_process
GO:0007588ExcretionTASbiological_process
GO:0007599HemostasisTASbiological_process
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0010628Positive regulation of gene expressionISSbiological_process
GO:0016021Integral component of membraneIEA NAScellular_component
GO:0021537Telencephalon developmentIEAbiological_process
GO:0031398Positive regulation of protein ubiquitinationNASbiological_process
GO:0032609Interferon-gamma productionIEAbiological_process
GO:0034097Response to cytokineIEAbiological_process
GO:0035811Negative regulation of urine volumeIEAbiological_process
GO:0035814Negative regulation of renal sodium excretionIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.57423595990.86224455380.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0550627013
GSE13712_SHEARDown-0.0496257015
GSE13712_STATICUp0.1211218812
GSE19018Up0.0104972382
GSE19899_A1Down-0.0339339993
GSE19899_A2Up0.0432785771
PubMed_21979375_A1Up0.0262074799
PubMed_21979375_A2Down-0.1799374472
GSE35957Up0.0686108048
GSE36640Down-0.0057758099
GSE54402Up0.0378077112
GSE9593Down-0.0206801901
GSE43922Up0.1524056509
GSE24585Up0.2377562301
GSE37065Up0.2487391610
GSE28863_A1Down-0.0069165158
GSE28863_A2Down-0.0850602102
GSE28863_A3Up0.1353958241
GSE28863_A4Up0.1575903901
GSE48662Down-0.0915717524

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DesmopressinDB00035 BTD00112 | BTD00061 | BIOD00112 | BIOD00061
VasopressinDB00067 BTD00110 | BIOD00110
ConivaptanDB00872 APRD01302
TerlipressinDB02638 EXPT03310
M0002DB05091 -
OPC-51803DB05838 -
TolvaptanDB06212 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.