HCSGD entry for PI4K2A

1. General information

Official gene symbolPI4K2A
Entrez ID55361
Gene full namephosphatidylinositol 4-kinase type 2 alpha
Other gene symbolsPI4KII PIK42A RP11-548K23.6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingNASmolecular_function
GO:0002561Basophil degranulationIEAbiological_process
GO:00044301-phosphatidylinositol 4-kinase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005739MitochondrionISScellular_component
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005768EndosomeISScellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006661Phosphatidylinositol biosynthetic processIDA TASbiological_process
GO:0016773Phosphotransferase activity, alcohol group as acceptorIEAmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0030425DendriteISScellular_component
GO:0030672Synaptic vesicle membraneIEAcellular_component
GO:0031083BLOC-1 complexIDAcellular_component
GO:0031410Cytoplasmic vesicleISScellular_component
GO:0031901Early endosome membraneIEAcellular_component
GO:0035651AP-3 adaptor complex bindingIDAmolecular_function
GO:0035838Growing cell tipISScellular_component
GO:0042734Presynaptic membraneISScellular_component
GO:0043005Neuron projectionISScellular_component
GO:0043025Neuronal cell bodyISScellular_component
GO:0043204PerikaryonIEAcellular_component
GO:0044231Host cell presynaptic membraneISScellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045121Membrane raftIDAcellular_component
GO:0046854Phosphatidylinositol phosphorylationIDAbiological_process
GO:0070382Exocytic vesicleIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02422298920.90987547210.36870630061.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5113502353
GSE13712_SHEARDown-0.1036904317
GSE13712_STATICDown-0.1301996486
GSE19018Down-0.1400023467
GSE19899_A1Up0.1860221142
GSE19899_A2Up0.2351994018
PubMed_21979375_A1Up1.0659244707
PubMed_21979375_A2Up1.2218520537
GSE35957Up0.1257944894
GSE36640Up1.0435394369
GSE54402Up0.2917930716
GSE9593Up0.9548284764
GSE43922Up0.0058255929
GSE24585Up0.1984177660
GSE37065Up0.0474467398
GSE28863_A1Down-0.3401047774
GSE28863_A2Up0.4046720490
GSE28863_A3Down-0.4747152135
GSE28863_A4Down-0.0357534359
GSE48662Up0.1348244509

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-128-3pMIMAT0000424MIRT021939MicroarrayFunctional MTI (Weak)17612493
hsa-miR-877-5pMIMAT0004949MIRT037358CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.