HCSGD entry for PPP5C
1. General information
| Official gene symbol | PPP5C |
|---|---|
| Entrez ID | 5536 |
| Gene full name | protein phosphatase 5, catalytic subunit |
| Other gene symbols | PP5 PPP5 PPT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004721 | Phosphoprotein phosphatase activity | IEA ISS | molecular_function |
| GO:0004722 | Protein serine/threonine phosphatase activity | TAS | molecular_function |
| GO:0004871 | Signal transducer activity | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006351 | Transcription, DNA-templated | TAS | biological_process |
| GO:0006470 | Protein dephosphorylation | IEA | biological_process |
| GO:0007067 | Mitosis | TAS | biological_process |
| GO:0007165 | Signal transduction | IMP | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0008289 | Lipid binding | IEA | molecular_function |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IMP | biological_process |
| GO:0043278 | Response to morphine | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051291 | Protein heterooligomerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4252165191 | 0.6020570191 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0840232683 |
| GSE13712_SHEAR | Down | -0.0668190744 |
| GSE13712_STATIC | Up | 0.0458296985 |
| GSE19018 | Up | 0.0440107424 |
| GSE19899_A1 | Down | -0.0873949152 |
| GSE19899_A2 | Up | 0.3383583389 |
| PubMed_21979375_A1 | Up | 0.3498713327 |
| PubMed_21979375_A2 | Down | -0.2811951890 |
| GSE35957 | Down | -0.1282327092 |
| GSE36640 | Down | -0.3326693434 |
| GSE54402 | Up | 0.1053334402 |
| GSE9593 | Down | -0.0609842270 |
| GSE43922 | Up | 0.3046846603 |
| GSE24585 | Down | -0.3354273267 |
| GSE37065 | Down | -0.0585961654 |
| GSE28863_A1 | Up | 0.2273236258 |
| GSE28863_A2 | Up | 0.0263437283 |
| GSE28863_A3 | Up | 0.2911436839 |
| GSE28863_A4 | Up | 0.0218020217 |
| GSE48662 | Up | 0.1455193886 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001518 | pSILAC | Functional MTI (Weak) | 18668040 |
| hsa-miR-99b-3p | MIMAT0004678 | MIRT038528 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039894 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
