HCSGD entry for TBC1D2
1. General information
| Official gene symbol | TBC1D2 |
|---|---|
| Entrez ID | 55357 |
| Gene full name | TBC1 domain family, member 2 |
| Other gene symbols | PARIS-1 PARIS1 TBC1D2A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005097 | Rab GTPase activator activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0016023 | Cytoplasmic membrane-bounded vesicle | IEA | cellular_component |
| GO:0030054 | Cell junction | IDA | cellular_component |
| GO:0031410 | Cytoplasmic vesicle | IDA | cellular_component |
| GO:0032851 | Positive regulation of Rab GTPase activity | IDA | biological_process |
| GO:0045296 | Cadherin binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0019024961 | 0.9226954827 | 0.1164548837 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1801256291 |
| GSE13712_SHEAR | Up | 1.1308415606 |
| GSE13712_STATIC | Up | 2.1408008171 |
| GSE19018 | Up | 0.0694942838 |
| GSE19899_A1 | Up | 0.5376849990 |
| GSE19899_A2 | Up | 0.5468239278 |
| PubMed_21979375_A1 | Up | 1.6343313859 |
| PubMed_21979375_A2 | Up | 1.5427939257 |
| GSE35957 | Up | 0.2723255984 |
| GSE36640 | Up | 1.1102261512 |
| GSE54402 | Down | -0.3064282868 |
| GSE9593 | Up | 1.3282597571 |
| GSE43922 | Up | 0.2564986233 |
| GSE24585 | Up | 0.4872019523 |
| GSE37065 | Down | -0.3493843321 |
| GSE28863_A1 | Down | -0.2335010671 |
| GSE28863_A2 | Up | 0.0605591933 |
| GSE28863_A3 | Down | -0.6484260880 |
| GSE28863_A4 | Up | 0.2519414825 |
| GSE48662 | Up | 0.1574630606 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | MIRT002537 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | NA | hsa-miR-373 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
