HCSGD entry for PPP2R5E
1. General information
| Official gene symbol | PPP2R5E |
|---|---|
| Entrez ID | 5529 |
| Gene full name | protein phosphatase 2, regulatory subunit B', epsilon isoform |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000159 | Protein phosphatase type 2A complex | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0008601 | Protein phosphatase type 2A regulator activity | IEA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9461827628 | 0.0743215645 | 0.9999902473 | 0.5138391019 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2210052988 |
| GSE13712_SHEAR | Down | -0.1643671669 |
| GSE13712_STATIC | Down | -0.2482129829 |
| GSE19018 | Up | 0.2827805661 |
| GSE19899_A1 | Down | -0.0294548748 |
| GSE19899_A2 | Down | -0.5799334938 |
| PubMed_21979375_A1 | Down | -0.4167142574 |
| PubMed_21979375_A2 | Down | -0.6077177551 |
| GSE35957 | Up | 0.0025423587 |
| GSE36640 | Down | -0.3947108040 |
| GSE54402 | Up | 0.0003229919 |
| GSE9593 | Down | -0.0449003620 |
| GSE43922 | Up | 0.0071326272 |
| GSE24585 | Up | 0.1253996208 |
| GSE37065 | Down | -0.1720190313 |
| GSE28863_A1 | Up | 0.1241988288 |
| GSE28863_A2 | Down | -0.4185553206 |
| GSE28863_A3 | Down | -0.0043361891 |
| GSE28863_A4 | Up | 0.1090164147 |
| GSE48662 | Down | -0.0808055677 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-365a-3p | MIMAT0000710 | MIRT044037 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045699 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051753 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051983 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
