HCSGD entry for UBE2W
1. General information
| Official gene symbol | UBE2W |
|---|---|
| Entrez ID | 55284 |
| Gene full name | ubiquitin-conjugating enzyme E2W (putative) |
| Other gene symbols | UBC-16 UBC16 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA IMP | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006513 | Protein monoubiquitination | IDA IMP | biological_process |
| GO:0006515 | Misfolded or incompletely synthesized protein catabolic process | ISS | biological_process |
| GO:0016881 | Acid-amino acid ligase activity | IEA | molecular_function |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0043161 | Proteasome-mediated ubiquitin-dependent protein catabolic process | ISS | biological_process |
| GO:0070979 | Protein K11-linked ubiquitination | IDA | biological_process |
| GO:0071218 | Cellular response to misfolded protein | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0360432050 | 0.9582859352 | 0.4316536331 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0825985390 |
| GSE13712_SHEAR | Up | 0.3387134464 |
| GSE13712_STATIC | Up | 0.2540087387 |
| GSE19018 | Up | 0.0433948172 |
| GSE19899_A1 | Up | 0.2913506743 |
| GSE19899_A2 | Up | 0.4170827396 |
| PubMed_21979375_A1 | Up | 0.7136964438 |
| PubMed_21979375_A2 | Up | 0.7517635964 |
| GSE35957 | Up | 0.5957962911 |
| GSE36640 | Up | 0.1659179649 |
| GSE54402 | Up | 0.4291180493 |
| GSE9593 | Up | 0.1667699171 |
| GSE43922 | Up | 0.2071646778 |
| GSE24585 | Up | 0.2451765530 |
| GSE37065 | Up | 0.1184022630 |
| GSE28863_A1 | Down | -0.3864782553 |
| GSE28863_A2 | Down | -0.4112062975 |
| GSE28863_A3 | Down | -0.3587320433 |
| GSE28863_A4 | Up | 0.0879501868 |
| GSE48662 | Up | 0.1608287937 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-142-3p | MIMAT0000434 | MIRT021613 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT021759 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021902 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024580 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026299 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028282 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
