HCSGD entry for PPP2R5D

1. General information

Official gene symbolPPP2R5D
Entrez ID5528
Gene full nameprotein phosphatase 2, regulatory subunit B', delta
Other gene symbolsB56D
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000159Protein phosphatase type 2A complexIEAcellular_component
GO:0002224Toll-like receptor signaling pathwayTASbiological_process
GO:0002755MyD88-dependent toll-like receptor signaling pathwayTASbiological_process
GO:0002756MyD88-independent toll-like receptor signaling pathwayTASbiological_process
GO:0004722Protein serine/threonine phosphatase activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusTAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006006Glucose metabolic processTASbiological_process
GO:0006096GlycolysisTASbiological_process
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0008601Protein phosphatase type 2A regulator activityIEAmolecular_function
GO:0016311DephosphorylationTASbiological_process
GO:0034134Toll-like receptor 2 signaling pathwayTASbiological_process
GO:0034138Toll-like receptor 3 signaling pathwayTASbiological_process
GO:0034142Toll-like receptor 4 signaling pathwayTASbiological_process
GO:0034146Toll-like receptor 5 signaling pathwayTASbiological_process
GO:0034162Toll-like receptor 9 signaling pathwayTASbiological_process
GO:0034166Toll-like receptor 10 signaling pathwayTASbiological_process
GO:0035666TRIF-dependent toll-like receptor signaling pathwayTASbiological_process
GO:0038123Toll-like receptor TLR1:TLR2 signaling pathwayTASbiological_process
GO:0038124Toll-like receptor TLR6:TLR2 signaling pathwayTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0050790Regulation of catalytic activityTASbiological_process
GO:0051403Stress-activated MAPK cascadeTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.29602151130.42902132140.99521729031.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0245081356
GSE13712_SHEARDown-0.0627495124
GSE13712_STATICDown-0.3025196430
GSE19018Up0.3747743528
GSE19899_A1Up0.1364920547
GSE19899_A2Up0.7265161596
PubMed_21979375_A1Up0.3255369308
PubMed_21979375_A2Down-0.0947424945
GSE35957Down-0.3699306741
GSE36640Down-0.2902289722
GSE54402Up0.1746601963
GSE9593Down-0.0834793072
GSE43922Up0.2431150880
GSE24585Down-0.4013961139
GSE37065Down-0.1908076215
GSE28863_A1Up0.1446376920
GSE28863_A2Up0.3559069267
GSE28863_A3Down-0.2289276597
GSE28863_A4Down-0.1778545776
GSE48662Up0.0844060616

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1914-5pMIMAT0007889MIRT035781CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT040037CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.