HCSGD entry for CASC1


1. General information

Official gene symbolCASC1
Entrez ID55259
Gene full namecancer susceptibility candidate 1
Other gene symbolsLAS1 PPP1R54
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005881Cytoplasmic microtubuleIEAcellular_component
GO:0008017Microtubule bindingIEAmolecular_function
GO:0048487Beta-tubulin bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.25283842940.89543805330.94274063381.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0951710743
GSE13712_SHEARDown-0.0305601877
GSE13712_STATICDown-0.0737869218
GSE19018Up0.3655009351
GSE19899_A1Up0.2576433353
GSE19899_A2Down-0.5078133100
PubMed_21979375_A1Up0.0614160291
PubMed_21979375_A2Up0.1318136376
GSE35957Up0.2565214805
GSE36640Up0.1106276672
GSE54402Up0.1162111323
GSE9593Down-0.1059854378
GSE43922Up0.0194052339
GSE24585Up0.6936002963
GSE37065Up0.0254726699
GSE28863_A1Down-0.0668895799
GSE28863_A2Down-0.0776145002
GSE28863_A3Up0.1240911445
GSE28863_A4Down-0.0042860474
GSE48662Down-0.0397360834

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.